Inexpensive High-Resolution, Single-Molecule Microscopy!
A research team developed a budget-friendly method for adapting confocal microscopes for Total Internal Reflection Fluorescence (TIRF) microscopy. Their paper is entitled “Economical Method to Construct a Prism-based TIRF Setup on an Existing Confocal Microscope to Perform smFRET Experiments.”
The paper presents “a simple and cost-effective method to build a prism-based TIRF setup on a laser scanning confocal microscope. The setup is affordable, and users can use both confocal and TIRF modes in the same setup with the same light source and optical components.”
The research setup used the following Chroma filters:
About Chroma Technology
Chroma Technology is a leading manufacturer and OEM supplier of high performance optical filters used in a wide range of applications, including health care, biomedical research, remote sensing, machine vision, and aerospace. Chroma offers an extensive selection of optical filter sets and filter accessories, as well as custom solutions tailored to customer-specific needs.
For more information or a quotation for this or other Chroma products, contact IL Photonics.